The rs738409 (I148M) variant of the PNPLA3 gene and cirrhosis: a meta-analysis
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چکیده
منابع مشابه
the analysis of the role of the speech acts theory in translating and dubbing hollywood films
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15 صفحه اولPNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis
BACKGROUND & AIMS Environmental and genetic factors contribute to alcoholic cirrhosis onset. In particular, age at exposure to liver stressors has been shown to be important in progression to fibrosis in hepatitis C individuals. However, no definite data on the role of age at onset of at-risk alcohol consumption are available. Moreover, patatin-like phospholipase domain-containing protein 3 (PN...
متن کاملAssociation between PNPLA3 rs738409 polymorphisms and risk of hepatocellular carcinoma and its development in patients with cirrhosis: a meta-analysis.
Genetic variants of PNPLA3 have been implicated in hepatocellular carcinoma (HCC) susceptibility; however, published findings have been both conflicting and inconclusive. To obtain a more precise estimate of the association of the PNPLA3 rs738409 (C > G) polymorphism with the overall risk of HCC and in patients with cirrhosis, we performed a meta-analysis of nine eligible studies identified thr...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2015
ISSN: 0022-2275
DOI: 10.1194/jlr.m048777